{"status":"OK","data":{"id":300200,"identifier":"SRT8RU","persistentUrl":"https://doi.org/10.34894/SRT8RU","protocol":"doi","authority":"10.34894","separator":"/","publisher":"DataverseNL","publicationDate":"2022-07-13","storageIdentifier":"surf://10.34894/SRT8RU","effectiveDatasetFileCountLimit":10000,"datasetFileUploadsAvailable":10000,"datasetType":"dataset","locks":[],"latestVersion":{"id":22073,"datasetId":300200,"datasetPersistentId":"doi:10.34894/SRT8RU","datasetType":"dataset","storageIdentifier":"surf://10.34894/SRT8RU","versionNumber":1,"internalVersionNumber":1691,"versionMinorNumber":0,"versionState":"RELEASED","latestVersionPublishingState":"RELEASED","deaccessionLink":"","lastUpdateTime":"2022-07-13T14:04:56Z","releaseTime":"2022-07-13T14:04:56Z","createTime":"2022-06-30T11:08:31Z","publicationDate":"2022-07-13","citationDate":"2022-07-13","effectiveDatasetFileCountLimit":10000,"datasetFileUploadsAvailable":10000,"license":{"name":"CC0-1.0","uri":"http://creativecommons.org/publicdomain/zero/1.0","iconUri":"https://licensebuttons.net/p/zero/1.0/88x31.png","rightsIdentifier":"CC0-1.0","rightsIdentifierScheme":"SPDX","schemeUri":"https://spdx.org/licenses/","languageCode":"en"},"fileAccessRequest":true,"metadataBlocks":{"citation":{"displayName":"Citation Metadata","name":"citation","fields":[{"typeName":"title","multiple":false,"typeClass":"primitive","value":"Evaluating the capabilities and challenges of layer-fMRI VASO at 3T"},{"typeName":"subtitle","multiple":false,"typeClass":"primitive","value":"Layer-fMRI VASO at 3T"},{"typeName":"author","multiple":true,"typeClass":"compound","value":[{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Huber, Renzo"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0002-3291-2202"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Kronbichler, Lisa"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Department of Psychiatry, Psychotherapy and Psychosomatics, Christian‐Doppler Medical Centre, PMU, Salzburg, Austria,"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0003-1659-706X"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Stirnberg, Rüdiger"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0001-7021-1063"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Ehses, Philipp"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0002-5839-6525"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Stöcker, Tony"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"German Center for Neurodegenerative Diseases (DZNE), Bonn, Germany"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0002-8946-9141"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Fernández-Cabello, Sara"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Norwegian Centre for Mental Disorders Research (NORMENT), Institute of Clinical Medicine, Uni Oslo, Oslo, Norway"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Poser, A Benedikt"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Faculty of Psychology and Neuroscience, Maastricht University, Maastricht, The Netherlands"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0001-8190-4367"}},{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Kronbichler, Martin"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"Neuroscience Institute, Christian Doppler Medical Centre, PMU, Salzburg, Austria"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"0000-0003-2240-2812"}}]},{"typeName":"datasetContact","multiple":true,"typeClass":"compound","value":[{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"faculty data manager FPN"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"Maastricht University"}},{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Huber, Renzo"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"Maastricht University"}}]},{"typeName":"dsDescription","multiple":true,"typeClass":"compound","value":[{"dsDescriptionValue":{"typeName":"dsDescriptionValue","multiple":false,"typeClass":"primitive","value":"<a>Study Abstract</a>:\nSub-millimeter functional imaging at ultrahigh field (UHF) strengths has the potential to capture cortical layer-specific functional information flow within and across brain systems. Recent sequence advancements of fMRI signal readout and contrast generations resulted in wide adaptation of layer-fMRI protocols across the global UHF neuroimaging community. However, most layer-fMRI applications are confined to one of ≈100 privileged UHF imaging centers, and sequence contrasts with unwanted sensitivity to large draining veins. In this work, we propose the application of vein-free vascular space occupancy (VASO) sequences at widely accessible 3T scanners. We aim to implement, characterize and apply a CBV-sensitive VASO sequence setup for 3T. We find that the longer T2*, and shorter T1 relaxation times at 3T can account for some of the lower z-magnetization in the inversion-recovery VASO sequence compared to 7T and 9.4T. Since 3T fMRI does not provide as much SNR compared to 7T, thermal-noise dominated layer-fMRI experiments at 3T require longer scan duration. In order to mitigate unrealistically long experiments, we aimed to increase the readout efficiency compared to previous 7T layer-fMRI VASO. This is done by means of utilizing fat saturation with binomial pulses, and segmented in-plane segmented trajectory, and externalizing phase navigators from the shot-specific readout. We test the utility of this setup for visual tasks, for motor tasks, and for movie watching tasks. We conclude that layer-fMRI VASO is applicable at 3T without too much further ado.\n\nLink to Zip file with all participants (96GB): https://layerfmri.page.link/3TVASO_groupdata"},"dsDescriptionDate":{"typeName":"dsDescriptionDate","multiple":false,"typeClass":"primitive","value":"2022-07-06"}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Medicine, Health and Life Sciences","Physics"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"layer-fMRI"}}]},{"typeName":"publication","multiple":true,"typeClass":"compound","value":[{"publicationCitation":{"typeName":"publicationCitation","multiple":false,"typeClass":"primitive","value":"in preparation"}}]},{"typeName":"language","multiple":true,"typeClass":"controlledVocabulary","value":["English"]},{"typeName":"grantNumber","multiple":true,"typeClass":"compound","value":[{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"Austrian Science Fund (FWF)"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"P 30390-B27"}},{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"Scientific Funds of the Paracelsus Medical University"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"E-13/18/097-KRO"}},{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"NWO VENI project"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"016.Veni.198.032"}},{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"NWO VIDI"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"16.Vidi.178.052"}},{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"H2020 FET-Open AROMA"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"88587"}}]},{"typeName":"depositor","multiple":false,"typeClass":"primitive","value":"Faculty of Psychology and Neuroscience - Maastricht University"},{"typeName":"dateOfDeposit","multiple":false,"typeClass":"primitive","value":"2022-06-30"},{"typeName":"kindOfData","multiple":true,"typeClass":"primitive","value":["fMRI data in nii format"]}]},"dansDataVaultMetadata":{"displayName":"Data Vault Metadata","name":"dansDataVaultMetadata","fields":[{"typeName":"dansDataversePid","multiple":false,"typeClass":"primitive","value":"doi:10.34894/SRT8RU"},{"typeName":"dansDataversePidVersion","multiple":false,"typeClass":"primitive","value":"1.0"},{"typeName":"dansBagId","multiple":false,"typeClass":"primitive","value":"urn:uuid:d8adf5f3-11a7-4c69-95ef-b55739fe0028"},{"typeName":"dansNbn","multiple":false,"typeClass":"primitive","value":"urn:nbn:nl:ui:13-14bdbda3-b4fa-4e48-841d-e5b251fe351d"}]}},"files":[]}}}