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The Data Sharing Agreement is signed by both parties.","citationRequirements":"Read <a href=\"https://www.umcutrecht.nl/en/research-data-umc-utrecht\">here</a>  for more information about the data request proces and the Data Sharing Agreement. The Data Sharing Agreement is signed by both parties.","conditions":"To access and use the dataset please read the Terms of Use and the Terms of Access for Restricted Files.","disclaimer":"Read <a href=\"https://www.umcutrecht.nl/en/research-data-umc-utrecht\">here</a>  for more information about the data request proces and the Data Sharing Agreement. The Data Sharing Agreement is signed by both parties.","termsOfAccess":"By downloading or otherwise accessing the materials, the downloader represents his/her acceptance of the Terms of Use. ","fileAccessRequest":false,"metadataBlocks":{"citation":{"displayName":"Citation Metadata","name":"citation","fields":[{"typeName":"title","multiple":false,"typeClass":"primitive","value":"A Phase 2, Comparative Randomised Trial to Evaluate the impact of reduced COVID-19 mRNA vaccination regimen on immunological responses and reactogenicity in paediatric subjects with prior SARS-CoV-2 immunity (CoVacc)"},{"typeName":"author","multiple":true,"typeClass":"compound","value":[{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Patricia Bruijning-Verhagen"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"UMC Utrecht"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"https://orcid.org/0000-0003-4105-9669"}}]},{"typeName":"datasetContact","multiple":true,"typeClass":"compound","value":[{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Julius Center for Health Sciences and Primary Care"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"UMC Utrecht"}},{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Bruijning-Verhagen, Patricia"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"UMC Utrecht"}},{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Nijland, Jeri"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"Ecraid"}}]},{"typeName":"dsDescription","multiple":true,"typeClass":"compound","value":[{"dsDescriptionValue":{"typeName":"dsDescriptionValue","multiple":false,"typeClass":"primitive","value":"Data from the CoVacc trial, a randomised two-arm trial comparing the two-dose COVID-19 vaccination regimen to a one-dose COVID-19 vaccination regimen in children 5-11 years of age with primed immunity in terms of immunogenicity (neutralizing antibodies & anti-RBD) and safety during (AEs) during a 12 month follow-up. A total of 31 subjects were included. Both single and two dose regimens induced robust and longlasting (up to 12 months) neutralizing and anti-RBD immune\nresponses, but non-inferiority of the single dose regimen could not be demonstrated. Both regimens also induced longlasting neutralizing responses to different VOCs, but titers were generally lower compared to SARS-CoV-2 wild-type. No new safety concerns were identified based on the safety analysis. \n\nThe data are sensitive since they involve personal information of patients. There are also restrictions on use by commercial parties, and on sharing openly based on (inter)national laws and regulations and written informed consent. Therefore these data (and additional clinical data) are only available upon signing a Data Sharing Agreement (see Terms of Access) and within a specially designed environment provided by the UMC Utrecht."},"dsDescriptionDate":{"typeName":"dsDescriptionDate","multiple":false,"typeClass":"primitive","value":"2025-01-21"}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Medicine, Health and Life Sciences"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"SARS-CoV-2"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"mRNA 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