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","contactForAccess":"Please fill out the <a href=\"https://www.umcutrecht.nl/en/data-request-form-umc-utrecht\">request form</a>.","fileAccessRequest":true,"metadataBlocks":{"citation":{"displayName":"Citation Metadata","name":"citation","fields":[{"typeName":"title","multiple":false,"typeClass":"primitive","value":"Highly multiplexed spatial analysis identifies tissue-resident memory T cells as drivers of ulcerative and immune checkpoint inhibitor induced colitis"},{"typeName":"author","multiple":true,"typeClass":"compound","value":[{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"van Eijs, Mick J.M."},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"UMC 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R script for data normalization, scaling, cell type annotation and analysis is publicly available at Zenodo (DOI: 10.5281/zenodo.7858216). In this Verse,\nraw data and corresponding meta data as outlined below have been deposited.<br><br>\nType of dataset: restricted data (template 3b)<br>\n===============================<br>\n\n<b>Imaging mass cytometry data (after single-cell segmentation)</b><br>\n\n-- segmented_IMC_data.Rda (restricted)<br>\nThis file contains the raw single-cell segmented channel data for all IMC channels including geometric cell data.<br>\n\n-- IMC_clinical_metadata.csv (restricted)<br>\nThis file contains clinical metadata for the subjects included in segmented_IMC_data.Rda<br>\n\n-- IMC_clinical_metadata_codebook.csv (unrestricted)<br>\nThis file contains codebook with description of all parameters included IMC_clinical_metadata.csv<br>\n\n<b>Serum multiplexed proteomic (Olink) data</b><br>\n\n-- Olink_data.csv (restricted)<br>\nThis file contains raw protein data (serum protein levels) and clinical metadata.<br>\n \n-- Olink_data_codebook.csv (unrestricted)<br>\nThis file contains codebook with description of all parameters included Olink_data.csv<br>\n\n- Patient informed consent form<br>\n-- PIF_v7_UNICIT.pdf (restricted)<br>\nThis file contains the original informed consent form that relates to the UNICIT biobank study as described in the original manuscript."},"dsDescriptionDate":{"typeName":"dsDescriptionDate","multiple":false,"typeClass":"primitive","value":"2023-04-24"}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Medicine, Health and Life Sciences"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Immune checkpoint inhibitor colitis"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Immune-related adverse event"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Ulcerative colitis"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Imaging mass cytometry"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Tissue-resident memory T cell"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"CD8+ T cell cytotoxicity"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Spatial proteomics"}},{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"Serum multiplex immunoassay"}}]},{"typeName":"depositor","multiple":false,"typeClass":"primitive","value":"van Eijs, Mick"},{"typeName":"dateOfDeposit","multiple":false,"typeClass":"primitive","value":"2023-04-24"}]},"dansDataVaultMetadata":{"displayName":"Data Vault 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