\r\n\r\nIntroduction: The primary aim of this study is to investigate the impact of a 13-week anomaly scan on the experienced levels of maternal anxiety and well-being. Secondly, to explore women’s knowledge on the possibilities and limitations of the scan and the preferred timing of screening for structural abnormalities.\r\n\r\n\r\n
Material and methods: In a prospective-cohort study conducted between 2013-2015, pregnant women in the North-Netherlands underwent a 13-week anomaly scan. Four online-questionnaires (Q1, Q2, Q3 and Q4) were completed before and after the 13- and the 20-week anomaly scans. In total, 1512 women consented to participate in the study and 1118 (74%) completed the questionnaires at Q1, 941 (64%) at Q2, 807 (55%) at Q3 and 535 (37%) at Q4. Psychological outcomes were measured by the state-trait inventory-scale (STAI), the patient’s positive-negative affect (PANAS) and ad-hoc designed questionnaires.\r\n\r\n\r\n
Results: Nine-nine percent of women wished to be informed as early as possible in pregnancy about the absence/presence of structural abnormalities. In 87% of women levels of knowledge on the goals and limitations of the 13-week anomaly scan were moderate-to-high. In women with a normal 13-week scan result, anxiety levels decreased (P<.001) and well-being increased over time (P<.001). In women with false-positive results (n=26), anxiety levels initially increased (STAI-Q1: 39.8 vs. STAI-Q2: 48.6, P =0.025), but later decreased around the 20-week anomaly scan (STAI-Q3: 36.4 vs. STAI-Q4: 34.2, P =0.36). \r\n\r\n\r\n
Conclusions: The 13-week scan did not negatively impact the psychological well-being of pregnant women. The small number of women with screen-positive results temporarily experienced higher anxiety after the scan but, in false-positive cases, anxiety levels normalized again when the abnormality was not confirmed at follow-up scans. Finally, most pregnant women have moderate-to-high levels of knowledge and strongly prefer early screening for fetal structural abnormalities."}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Medicine, Health and Life Sciences"]},{"typeName":"topicClassification","multiple":true,"typeClass":"compound","value":[{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"Prenatal Diagnosis"},"topicClassVocab":{"typeName":"topicClassVocab","multiple":false,"typeClass":"primitive","value":"MeSH"},"topicClassVocabURI":{"typeName":"topicClassVocabURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/meshhome.html"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"Ultrasonography"},"topicClassVocab":{"typeName":"topicClassVocab","multiple":false,"typeClass":"primitive","value":"MeSH"},"topicClassVocabURI":{"typeName":"topicClassVocabURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/meshhome.html"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"Nuchal Translucency Measurement"},"topicClassVocab":{"typeName":"topicClassVocab","multiple":false,"typeClass":"primitive","value":"MeSH"},"topicClassVocabURI":{"typeName":"topicClassVocabURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/meshhome.html"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"Maternal Health"},"topicClassVocab":{"typeName":"topicClassVocab","multiple":false,"typeClass":"primitive","value":"MeSH"},"topicClassVocabURI":{"typeName":"topicClassVocabURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/meshhome.html"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"Test Anxiety Scale"},"topicClassVocab":{"typeName":"topicClassVocab","multiple":false,"typeClass":"primitive","value":"MeSH"},"topicClassVocabURI":{"typeName":"topicClassVocabURI","multiple":false,"typeClass":"primitive","value":"https://www.nlm.nih.gov/mesh/meshhome.html"}}]},{"typeName":"publication","multiple":true,"typeClass":"compound","value":[{"publicationCitation":{"typeName":"publicationCitation","multiple":false,"typeClass":"primitive","value":"Bardi F, Bakker M, Kenkhuis MJA, Ranchor AV, Bakker MK, Elvan A, et al. (2021) Psychological outcomes, knowledge and preferences of pregnant women on first-trimester screening for fetal structural abnormalities: A prospective cohort study. PLoS ONE 16(1): e0245938. https://doi.org/10.1371/journal.pone.0245938"},"publicationIDType":{"typeName":"publicationIDType","multiple":false,"typeClass":"controlledVocabulary","value":"doi"},"publicationIDNumber":{"typeName":"publicationIDNumber","multiple":false,"typeClass":"primitive","value":"10.1371/journal.pone.0245938"},"publicationURL":{"typeName":"publicationURL","multiple":false,"typeClass":"primitive","value":"https://doi.org/10.1371/journal.pone.0245938"}}]},{"typeName":"language","multiple":true,"typeClass":"controlledVocabulary","value":["English"]},{"typeName":"depositor","multiple":false,"typeClass":"primitive","value":"Bardi, Francesca"},{"typeName":"dateOfDeposit","multiple":false,"typeClass":"primitive","value":"2020-10-28"}]},"dansDataVaultMetadata":{"displayName":"Data Vault Metadata","name":"dansDataVaultMetadata","fields":[{"typeName":"dansDataversePid","multiple":false,"typeClass":"primitive","value":"doi:10.34894/HDRQJA"},{"typeName":"dansDataversePidVersion","multiple":false,"typeClass":"primitive","value":"1.2"},{"typeName":"dansBagId","multiple":false,"typeClass":"primitive","value":"urn:uuid:299bdfc7-bdbf-48c5-a517-5b229f11bb22"},{"typeName":"dansNbn","multiple":false,"typeClass":"primitive","value":"urn:nbn:nl:ui:13-1a98e608-9bdf-40f3-9292-1debe675a7bd"}]}},"files":[{"label":"Minimal dataset for results.sav","restricted":false,"version":1,"datasetVersionId":3411,"dataFile":{"id":39390,"persistentId":"","filename":"Minimal dataset for results.sav","contentType":"application/x-spss-sav","friendlyType":"SPSS Binary","filesize":349686,"storageIdentifier":"surf://store:17575d04d33-6116ad3eb9e5","rootDataFileId":-1,"checksum":{"type":"SHA-1","value":"a110350c4067a9adcb248b39e7d2788432768adb"},"tabularData":false,"creationDate":"2020-10-29","publicationDate":"2021-01-13","lastUpdateTime":"2021-01-29T07:57:22Z","fileAccessRequest":false}}]}}}