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Access for research purposes only. Please submit your application for access to the researcher.","restrictions":"Access for research purposes only. Please submit your application for access to the researcher.","fileAccessRequest":false,"metadataBlocks":{"citation":{"displayName":"Citation Metadata","name":"citation","fields":[{"typeName":"title","multiple":false,"typeClass":"primitive","value":"Cognitive function and radiation"},{"typeName":"author","multiple":true,"typeClass":"compound","value":[{"authorName":{"typeName":"authorName","multiple":false,"typeClass":"primitive","value":"Barazzuol, Lara"},"authorAffiliation":{"typeName":"authorAffiliation","multiple":false,"typeClass":"primitive","value":"University of Groningen"},"authorIdentifierScheme":{"typeName":"authorIdentifierScheme","multiple":false,"typeClass":"controlledVocabulary","value":"ORCID"},"authorIdentifier":{"typeName":"authorIdentifier","multiple":false,"typeClass":"primitive","value":"https://orcid.org/0000-0002-6538-2383"}}]},{"typeName":"datasetContact","multiple":true,"typeClass":"compound","value":[{"datasetContactName":{"typeName":"datasetContactName","multiple":false,"typeClass":"primitive","value":"Research Data Office"},"datasetContactAffiliation":{"typeName":"datasetContactAffiliation","multiple":false,"typeClass":"primitive","value":"University of Groningen"}}]},{"typeName":"dsDescription","multiple":true,"typeClass":"compound","value":[{"dsDescriptionValue":{"typeName":"dsDescriptionValue","multiple":false,"typeClass":"primitive","value":"This dataset contains results collected in a pre-clinical project that looks at the effect of radiation on neurocognitive function using an animal model.\r\n\r\nRadiotherapy remains a mainstay in the management of adult brain tumours. Unfortunately, 50 to 90% of the surviving patients develop progressive neurocognitive dysfunction severely affecting quality of life. The pathogenesis of radiation-induced neurocognitive dysfunction is not well understood. In this dataset we developed a pre-clinical animal model to assess the effect of whole brain and partial brain irradiation on neurocognitive outcome. Data include results from behavioural tests assessing memory, learning and locomotor function, as well as some initial data on PET imaging and the histological analysis of brain tissues."}}]},{"typeName":"subject","multiple":true,"typeClass":"controlledVocabulary","value":["Medicine, Health and Life Sciences"]},{"typeName":"keyword","multiple":true,"typeClass":"compound","value":[{"keywordValue":{"typeName":"keywordValue","multiple":false,"typeClass":"primitive","value":"radiotherapy"}}]},{"typeName":"topicClassification","multiple":true,"typeClass":"compound","value":[{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"neurocognitive function"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"brain damage"}},{"topicClassValue":{"typeName":"topicClassValue","multiple":false,"typeClass":"primitive","value":"radiotherapy"}}]},{"typeName":"grantNumber","multiple":true,"typeClass":"compound","value":[{"grantNumberAgency":{"typeName":"grantNumberAgency","multiple":false,"typeClass":"primitive","value":"ZonMW Off-Road project"},"grantNumberValue":{"typeName":"grantNumberValue","multiple":false,"typeClass":"primitive","value":"451001001"}}]},{"typeName":"depositor","multiple":false,"typeClass":"primitive","value":"Goldberg, Maarten"},{"typeName":"dateOfDeposit","multiple":false,"typeClass":"primitive","value":"2020-02-13"},{"typeName":"kindOfData","multiple":true,"typeClass":"primitive","value":["Data include neurocognitive function as measured using a panel of behavioural tests at different time points after irradiation. Additionally, this dataset include initial data on the relative 18FDG-PET imaging and histological analysis.","File types: Data analysis (.xcls and .pzfx), and supportive behavioural test videos (.mpg), PET images () and histological images (.jpeg, .tiff or .png).","File size: 2-3 Gb supportive/representative videos and images"]}]},"dansDataVaultMetadata":{"displayName":"Data Vault Metadata","name":"dansDataVaultMetadata","fields":[{"typeName":"dansDataversePid","multiple":false,"typeClass":"primitive","value":"doi:10.34894/0MG3ZU"},{"typeName":"dansDataversePidVersion","multiple":false,"typeClass":"primitive","value":"1.0"},{"typeName":"dansBagId","multiple":false,"typeClass":"primitive","value":"urn:uuid:561a5217-982f-42b6-bc90-4356a52121ad"},{"typeName":"dansNbn","multiple":false,"typeClass":"primitive","value":"urn:nbn:nl:ui:13-e3027ecc-ad99-4036-8d05-9da35f949914"}]}},"files":[]}}}